Long-term Outcomes of Pediatric-Onset Hypertrophic Cardiomyopathy and Age-Specific Risk Factors for Lethal Arrhythmic Events.

ABSTRACT:

Importance

Predictors of lethal arrhythmic events (LAEs) after a pediatric diagnosis of hypertrophic cardiomyopathy (HCM) are unresolved. Existing algorithms for risk stratification are limited to patients older than 16 years because of a lack of data on younger individuals.

Objective

To describe the long-term outcome of pediatric-onset HCM and identify age-specific arrhythmic risk factors.

Design, setting, and participants

This study assessed patients with pediatric-onset hypertrophic cardiomyopathy diagnosed from 1974 to 2016 in 2 national referral centers for cardiomyopathies in Florence, Italy. Patients with metabolic and syndromic disease were excluded.

Exposures

Patients were assessed at 1-year intervals, or more often, if their clinical condition require

SUBMITTER: Maurizi N 

PROVIDER: S-EPMC6128509 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature