Pregnancy complications and subsequent breast cancer risk in the mother: a Nordic population-based case-control study.

ABSTRACT: Certain features of pregnancy are important risk factors for breast cancer, such as protection afforded by young age at first birth. Preeclampsia, a pregnancy complication, is associated with reduced maternal breast cancer risk. However, questions remain regarding causality, biological mechanisms and the relation of other hypertensive conditions to risk. We conducted a population-based case-control study of breast cancer cases (n = 116,196) in parous women identified through linkage of birth and cancer registries in Denmark, Finland, Norway and Sweden (1967-2013), including up to 10 matched controls per case (n = 1,147,192) sampled from the birth registries (complete data were not available on all variables). Odds ratios (ORs) with 95% confidence intervals (CIs) were derived from unconditi

SUBMITTER: Troisi R 

PROVIDER: S-EPMC6128759 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature