Association between Hashimoto's thyroiditis and cholelithiasis: a retrospective cohort study in Taiwan.

ABSTRACT:

Objective

To investigate the relation of Hashimoto's thyroiditis (HT) to cholelithiasis and cholecystectomy in a retrospective population-based study.

Setting

Cohort study.

Participants

We identified 1268 patients aged ≥20 years with HT between 2000 and 2010 as the study cohort.

Primary and secondary outcome measures

Patients without HT were randomly selected from a database and propensity-matched with the study cohort at a 1:4 ratio according to age, sex, comorbidities and year of the index date to measure the incidence of cholelithiasis and cholecystectomy.

Results

The cumulative incidence of cholelithiasis was higher in the HT cohort than that in the non-HT cohort (log-rank test, p<0.001), with a 1.91-fold higher risk of choleithiasis (95% CI 1.58 to

SUBMITTER: Chen CH 

PROVIDER: S-EPMC6129049 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature