Phototherapy for neonatal hyperbilirubinemia and childhood eczema, rhinitis and wheeze.

ABSTRACT:

Background

The pathogenesis of allergic diseases in childhood may be attributed to influences of early environmental stimuli on fetal and neonatal immune regulation. Neonatal hyperbilirubinemia is common in the Asian population and up to 20% of infants require phototherapy. We examined the hypothesis that phototherapy for neonatal hyperbilirubinemia modulates the infant's risk of developing eczema, rhinitis and wheeze in the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort.

Method

Interviewers collected information on demographics, lifestyle, birth data and allergic outcomes. Atopic sensitization was assessed through skin prick testing (SPT) to aeroallergens and food allergens.

Results

A total of 135 (12.8%) children underwent phototherapy for neo

SUBMITTER: Tham EH 

PROVIDER: S-EPMC6129174 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature