Predictive Value of T _peak - T _end Indices for Adverse Outcomes in Acquired QT Prolongation: A Meta-Analysis.

ABSTRACT: Background: Acquired QT interval prolongation has been linked with malignant ventricular arrhythmias, such as torsade de pointes, in turn predisposing to sudden cardiac death. Increased dispersion of repolarization has been identified as a pro-arrhythmic factor and can be observed as longer T_peak - T_end interval and higher T_peak - T_end/QT ratio on the electrocardiogram. However, the values of these repolarization indices for predicting adverse outcomes in this context have not been systematically evaluated. Method: PubMed, Embase and Cochrane Library databases were searched until 14th February 2018, identifying 232 studies. Results: Five studies on acquired QT prolongation met the inclusion criteria and 308 subjects wi

SUBMITTER: Tse G 

PROVIDER: S-EPMC6129769 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature