Isolated systolic hypertension of the young and its association with central blood pressure in a large multi-ethnic population. The HELIUS study.

ABSTRACT: Background Isolated systolic hypertension (ISH) of the young has been associated with both normal and increased cardiovascular risk, which has been attributed to differences in central systolic blood pressure and arterial stiffness. Methods We assessed the prevalence of ISH of the young and compared differences in central systolic blood pressure and arterial stiffness between ISH and other hypertensive phenotypes in a multi-ethnic population of 3744 subjects (44% men), aged <40 years, participating in the HELIUS study. Results The overall prevalence of ISH was 2.7% (5.2% in men and 1.0% in women) with the highest prevalence in individuals of African descent. Subjects with ISH had lower central systolic blood pressure and pulse wave velocity compared with those with isolated diastolic or sy

SUBMITTER: Eeftinck Schattenkerk DW 

PROVIDER: S-EPMC6130124 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature