Protracted development of executive and mnemonic brain systems underlying working memory in adolescence: A longitudinal fMRI study.

ABSTRACT: Working memory (WM), the ability to hold information on-line to guide planned behavior, improves through adolescence in parallel with continued maturation of critical brain systems supporting cognitive control. Initial developmental neuroimaging studies with one or two timepoints have provided important though varied results limiting our understanding of which and how neural systems change during this transition into mature WM. In this study, we leverage functional magnetic resonance imaging (fMRI) longitudinal data spanning up to 9 years in 129 normally developing individuals to identify which systems demonstrate growth changes that accompany improvements in WM performance. We used a memory guided saccade task that allowed us to probe encoding, pure maintenance, and retrieval neural proce

SUBMITTER: Simmonds DJ 

PROVIDER: S-EPMC6130258 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature