Challenging obesity, diabetes, and addiction: the potential of lorcaserin extended release.

ABSTRACT: Obesity is a global epidemic that is a leading cause of preventable death. In addition to lifestyle modification, there are numerous obesity treatments for clinicians to consider, including medications. Lorcaserin immediate release/extended release (IR/XR) is a US Food and Drug Administration approved medication for overweight and obese patients to be used with lifestyle modifications. Lorcaserin is thought to reduce weight by targeting the serotonin (5HT_2c) system to induce satiety. Lorcaserin IR has been shown to be effective in reducing weight in overweight (body mass index [BMI] > 27 kg/m²) and obese (BMI > 30 kg/m²) participants in three large Phase III trials. In addition, lorcaserin has been shown to reduce post-cessation weight gain and improved smo

SUBMITTER: Hurt RT 

PROVIDER: S-EPMC6130259 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature