Surgical intervention may be a therapeutic option for NSCLC patients with AJCC stage IV: a large population-based study.

ABSTRACT:

Background

Few studies have focused on the role of surgery in the treatment of stage IV non-small cell lung cancer (NSCLC). In our study, we mainly focused on the surgical therapeutic option for NSCLC patients with American Joint Committee on Cancer stage IV.

Patients and methods

Using the Surveillance Epidemiology and End Results database, we screened out an appropriate patient population with stage IV NSCLC treated between 2004 and 2013. Kaplan-Meier curve analysis was used to compare the survival between patients receiving surgery and standard of care. The effect of surgery on primary and regional/distant sites on overall survival (OS) was further evaluated by Cox proportional hazard model. Finally, subgroup analysis based on patient and disease variables was conducted by

SUBMITTER: Wang H 

PROVIDER: S-EPMC6130287 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature