Antifungal and antiproliferative activities of endophytic fungi isolated from the leaves of Markhamia tomentosa.

ABSTRACT:

Context

Plants harbor endophytes with potential bioactivity. Markhamia tomentosa (Benth) K. Schum ex. Engl. (Bignoniaceae) is reported to possess antioxidant, anti-inflammatory and anticancer activities.

Objective

The antifungal and antiproliferative properties of endophytic fungi extracts and fractions from M. tomentosa were evaluated.

Material and methods

Endophytic fungi were isolated from the leaves of M. tomentosa and identified by ITS-rDNA sequence analysis. The antagonistic effect of the fungal strains was investigated against pathogenic fungi viz, Fusarium oxysporum, Sclerotinia sclerotiorium, Rhizoctonia solani, and Botrytis cinerea using the dual culture assay for 5-7 days. Antiproliferative effect of the fungal extracts and fractions (3.91-250 μg/mL) on HeL

SUBMITTER: Ibrahim M 

PROVIDER: S-EPMC6130725 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature