A health state utility valuation study to assess the impact of treatment mode of administration in Gaucher disease.

ABSTRACT:

Background

This study aimed to obtain UK societal-based utility values for health states related to treatment mode of administration using Gaucher disease as the background condition.

Methods

A review of relevant literature and expert clinical input informed the development of five health states characterising the impact of Gaucher disease and its management on patients' lives. A base-state characterising the "controlled disease" was developed as well as four subsequent health states which varied in description of the method (intravenous versus oral) and frequency of treatment administration. Health state utilities were obtained using the time trade-off (TTO) method via face-to-face interviews with 100 members from the UK general population. Before the valuation exercise, pa

SUBMITTER: Hadi M 

PROVIDER: S-EPMC6131903 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature