Intrafamilial oocyte donation in classic galactosemia: ethical and societal aspects.

ABSTRACT: Classic galactosemia is a rare inherited disorder of galactose metabolism. Primary ovarian insufficiency (POI) with subfertility affects > 80% of female patients and is an important concern for patients and their parents. Healthcare providers are often consulted for subfertility treatment possibilities. An option brought up by the families is intrafamilial oocyte donation (mother-to-daughter or sister-to-sister). In addition to POI, galactosemia patients can also present varying cognitive and neurological impairments, which may not be fully clear at the time when mother-to-daughter oocyte donation is considered. Ethical and societal aspects arise when exploring this option. This study aimed to provide guidance in aspects to consider based on the views of different groups involved in the oo

SUBMITTER: Haskovic M 

PROVIDER: S-EPMC6133175 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature