Altered long noncoding RNAs and survival outcomes in ovarian cancer: A systematic review and meta-analysis (PRISMA Compliant).

ABSTRACT:

Background

Previous studies investigating the association between altered long noncoding RNAs (lncRNAs) and survival outcomes in ovarian cancer have obtained controversial results. To comprehensively evaluate the association, we conducted a systematic review and meta-analysis of the studies published on the subject.

Methods

We performed a systematic search using the databases of the Cochrane Central Register of Controlled Trials, PubMed, and Embase to find all relevant articles from inception to May 7, 2017. Studies that evaluated the association between 1 specific lncRNA and survival outcomes in ovarian cancer were included. Pooled hazard ratios (HRs) and 95% confidence intervals (95% CIs) for overall survival, progression-free survival, and disease-free survival were calcu

SUBMITTER: Ning L 

PROVIDER: S-EPMC6133440 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature