HLA-DRB1 polymorphisms and alopecia areata disease risk: A systematic review and meta-analysis.

ABSTRACT:

Background

Published studies have reported conflicting and heterogeneous results regarding the association between human leukocyte antigen (HLA)-DRB1 polymorphisms and alopecia areata (AA). This study aimed to review and quantitatively analyze the association between HLA-DRB1 polymorphisms and AA.

Methods

In this study, all relevant publications were searched through December 2016. Odds ratios (ORs) and confidence intervals (CIs) for comparisons between case and control groups were calculated. Stata 14.0 software was used to perform statistical analysis. This research does not require formal ethical approval because the data used in this analysis do not involve personal information and thus do not affect privacy.

Results

Twelve articles were identified. For HLA-DRB1*0

SUBMITTER: Ji C 

PROVIDER: S-EPMC6133534 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature