Dose-Response Effects of Tai Chi and Physical Therapy Exercise Interventions in Symptomatic Knee Osteoarthritis.

ABSTRACT:

Background

Therapeutic exercise is a currently recommended nonpharmacological treatment for knee osteoarthritis (KOA). The optimal treatment dose (frequency or duration) has not been determined.

Objective

To examine dose-response relationships, minimal effective dose, and baseline factors associated with the timing of response from 2 exercise interventions in KOA.

Design

Secondary analysis of a single-blind, randomized trial comparing 12-week Tai Chi and physical therapy exercise programs (Trial Registry #NCT01258985).

Setting

Urban tertiary care academic hospital PARTICIPANTS: A total of 182 participants with symptomatic KOA (mean age 61 years; BMI 32 kg/m², 70% female; 55% white).

Methods

We defined dose as cumulative attendance-weeks of int

SUBMITTER: Lee AC 

PROVIDER: S-EPMC6134181 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature