The complex human urinary sugar profile: determinants revealed in the cross-sectional KarMeN study.

ABSTRACT:

Background

Although sugars and sugar derivatives are an important class of metabolites involved in many physiologic processes, there is limited knowledge on their occurrence and pattern in biofluids.

Objective

Our aim was to obtain a comprehensive urinary sugar profile of healthy participants and to demonstrate the wide applicability and usefulness of this sugar profiling approach for nutritional as well as clinical studies.

Design

In the cross-sectional KarMeN study, the 24-h urine samples of 301 healthy participants on an unrestricted diet, assessed via a 24-h recall, were analyzed by a newly developed semitargeted gas chromatography-mass spectrometry (GC-MS) profiling method that enables the detection of known and unknown sugar compounds. Statistical analyses were

SUBMITTER: Mack CI 

PROVIDER: S-EPMC6134285 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature