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Feasibility of Bioengineered Tracheal and Bronchial Reconstruction Using Stented Aortic Matrices.


ABSTRACT:

Importance

Airway transplantation could be an option for patients with proximal lung tumor or with end-stage tracheobronchial disease. New methods for airway transplantation remain highly controversial.

Objective

To establish the feasibility of airway bioengineering using a technique based on the implantation of stented aortic matrices.

Design, setting, and participants

Uncontrolled single-center cohort study including 20 patients with end-stage tracheal lesions or with proximal lung tumors requiring a pneumonectomy. The study was conducted in Paris, France, from October 2009 through February 2017; final follow-up for all patients occurred on November 2, 2017.

Exposures

Radical resection of the lesions was performed using standard surgical techniques. After res

SUBMITTER: Martinod E 

PROVIDER: S-EPMC6134437 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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