Dynamics of Afebrile Plasmodium falciparum Infections in Mozambican Men.

ABSTRACT:

Background

Afebrile Plasmodium falciparum infections usually remain undetected and untreated in the community and could potentially contribute to sustaining local malaria transmission in areas aiming for malaria elimination.

Methods

Thirty-two men with afebrile P. falciparum infections detected with rapid diagnostic test (RDTs) were followed for 28 days. Kaplan-Meier estimates were computed to estimate probability of parasite positivity and of reducing parasitemia by half of its initial level by day 28. Trends of parasite densities quantified by microscopy and real-time quantitative polymerase chain reaction (qPCR) were assessed using Poisson regression models, and the microscopy-to-qPCR positivity ratio was calculated at each time point. Three survival distributions (Gomper

SUBMITTER: Galatas B 

PROVIDER: S-EPMC6137111 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature