Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis: A Systematic Review, Meta-analysis, and Meta-regression.

ABSTRACT:

Importance

The value of early intervention in psychosis and allocation of public resources has long been debated because outcomes in people with schizophrenia spectrum disorders have remained suboptimal.

Objective

To compare early intervention services (EIS) with treatment as usual (TAU) for early-phase psychosis.

Data sources

Systematic literature search of PubMed, PsycINFO, EMBASE, and ClinicalTrials.gov without language restrictions through June 6, 2017.

Study selection

Randomized trials comparing EIS vs TAU in first-episode psychosis or early-phase schizophrenia spectrum disorders.

Data extraction and synthesis

This systematic review was conducted according to PRISMA guidelines. Three independent investigators extracted data for a random-effects meta

SUBMITTER: Correll CU 

PROVIDER: S-EPMC6137532 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature