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Predictive factors for multidrug-resistant gram-negative bacteria among hospitalised patients with complicated urinary tract infections.


ABSTRACT:

Background

Patients with complicated urinary tract infections (cUTIs) frequently receive broad-spectrum antibiotics. We aimed to determine the prevalence and predictive factors of multidrug-resistant gram-negative bacteria in patients with cUTI.

Methods

This is a multicenter, retrospective cohort study in south and eastern Europe, Turkey and Israel including consecutive patients with cUTIs hospitalised between January 2013 and December 2014. Multidrug-resistance was defined as non-susceptibility to at least one agent in three or more antimicrobial categories. A mixed-effects logistic regression model was used to determine predictive factors of multidrug-resistant gram-negative bacteria cUTI.

Results

From 948 patients and 1074 microbiological isolates, Escherichia c

SUBMITTER: Gomila A 

PROVIDER: S-EPMC6137881 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature