Prescription patterns of angiotensin-converting enzyme inhibitors for various indications: A UK population-based study.

ABSTRACT:

Aim

Angiotensin-converting enzyme inhibitors (ACEIs) are widely prescribed for several cardiovascular indications. This study investigated patterns of ACEI use for various indications.

Methods

A descriptive, retrospective population-based study was conducted using data from the UK Clinical Practice Research Datalink. Patients starting ACEIs (2007-2014) were selected and ACEI indications were retrieved from electronically recorded medical records. Stratified by indication, we distinguished between persistent and nonpersistent ACEI use, considering a 6-month interval between two prescription periods as a maximum for persistent use. Five-year persistence rates for various indications were calculated using the Kaplan-Meier method and compared in a log-rank test. Nonpersistent us

SUBMITTER: Mahmoudpour SH 

PROVIDER: S-EPMC6138483 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature