The emerging risk of exposure to air pollution on cognitive decline and Alzheimer's disease - Evidence from epidemiological and animal studies.

ABSTRACT: As incidence of Alzheimer's disease (AD) and other neurodegenerative diseases rise, there is increasing interest in environmental factors which may contribute to disease onset and progression. Air pollution has been known as a major health hazard for decades. While its effects on cardiopulmonary morbidity and mortality have been extensively studied, growing evidence has emerged that exposure to polluted air is associated with impaired cognitive functions at all ages and increased risk of AD and other dementias in later life; this association is particularly notable with traffic related pollutants such as nitrogen dioxide, nitrous oxide, black carbon, and small diameter airborne solids and liquids known as particulate matter. The exact mechanisms by which air pollutants mediate neurotoxicit

SUBMITTER: Kilian J 

PROVIDER: S-EPMC6138768 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature