Patterns of cognitive function in middle-aged and elderly Chinese adults-findings from the EMCOA study.

ABSTRACT:

Background

The principal aim of this study was to demonstrate the gender-specific cognitive patterns among middle-aged and elderly Chinese adults, investigate the risk factors on global and domain-specific cognitive performance in men and women, respectively, and report demographically adjusted norms for cognitive tests.

Methods

The Effects and Mechanism of Cholesterol and Oxysterol on Alzheimer's disease (EMCOA) study enrolled 4573 participants aged 50-70 years in three Chinese cities. All participants underwent an extensive neuropsychological test battery. Composite scores for specific domains were derived from principal component analysis (PCA). Multivariate linear regression models were used to determine gender-specific risk factors and demographically adjusted normative

SUBMITTER: An Y 

PROVIDER: S-EPMC6138914 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature