Inverse association of MRI-derived native myocardial T1 and perfusion reserve index in women with evidence of ischemia and no obstructive CAD: A pilot study.

ABSTRACT:

Background

It has recently been shown that magnetic resonance (MR) "native T1" mapping is capable of characterizing abnormal microcirculation in patients with obstructive coronary artery disease (CAD). In studies involving women with signs and symptoms of ischemia and no obstructive CAD (INOCA), however, the potential role of native T1 as an imaging marker and its association with indices of diastolic function or vasodilator-induced myocardial ischemia have not been explored. We investigated whether native T1 in INOCA is associated with reduced myocardial perfusion reserve index (MPRI) or with diastolic dysfunction.

Methods

Twenty-two female patients with INOCA and twelve female reference controls with matching age and body-mass index were studied. The patients had evidence

SUBMITTER: Shaw JL 

PROVIDER: S-EPMC6139276 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature