The interplay of childhood behavior problems and IQ in the development of later schizophrenia and affective psychoses.

ABSTRACT: Schizophrenia and affective psychoses are both associated with impaired social functioning, but the extent to which childhood behavioral impairments are present prior to onset of illness is less well studied. Moreover, the concurrent relationship of childhood behavior problems and premorbid IQ with subsequent psychotic disorder has not been established. We investigated whether childhood behavior problems are associated with increased risk for adult schizophrenia or affective psychosis, independently and in combination with IQ. The study included individuals with schizophrenia (N=47), affective psychoses (N=45) and non-psychotic controls (N=1496) from the New England Family Study. Behavior problems were prospectively assessed from standardized clinician observations at ages 4 and 7. IQ was

SUBMITTER: Agnew-Blais J 

PROVIDER: S-EPMC6140330 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature