Dementia, Alzheimer's Disease, and Mortality after Hemodialysis Initiation.

ABSTRACT:

Background and objectives

Older patients with ESKD experience rapid declines in executive function after initiating hemodialysis; these impairments might lead to high rates of dementia and Alzheimer's disease in this population. We estimated incidence, risk factors, and sequelae of diagnosis with dementia and Alzheimer's disease among older patients with ESKD initiating hemodialysis.

Design, setting, participants, & measurements

We studied 356,668 older (age ≥66 years old) patients on hemodialysis (January 1, 2001 to December 31, 2013) from national registry data (US Renal Data System) linked to Medicare. We estimated the risk (cumulative incidence) of diagnosis of dementia and Alzheimer's disease and studied factors associated with these disorders using competing risks mode

SUBMITTER: McAdams-DeMarco MA 

PROVIDER: S-EPMC6140560 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature