Autoimmune retinopathy and optic neuropathy associated with enolase-positive renal oncocytoma.

ABSTRACT:

Purpose

To report a case of autoimmune retinopathy and optic neuropathy associated with an enolase-positive renal oncocytoma.

Observations

A 41-year-old man presented with subacute, painless, bilateral vision loss. On initial examination, visual acuity measured 20/125 OD and 20/1250 OS, and telangiectatic vessels were noted on the optic nerves and in the maculae. Goldmann perimetry showed bilateral, cecocentral scotomas, and electroretinography demonstrated reduced photopic and scotopic signals, concerning for autoimmune retinopathy. Serum testing showed multiple positive anti-optic nerve and anti-retinal antibodies, including to alpha-enolase. Extensive systemic workup was negative except for a large, exophytic, right renal mass. Biopsy was consistent with a benign oncocyto

SUBMITTER: Cheng JL 

PROVIDER: S-EPMC6140802 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature