HPLC-ESI-MS method for C₆₀ fullerene mitochondrial content quantification.

ABSTRACT: The presented dataset describes the quantification of carbon nanoparticle C₆₀ fullerene accumulated in mitochondria of human leukemic cells treated with nanostructure. Firstly, the high performance liquid chromatography-electro spray ionization-mass spectrometry (HPLC-ESI-MS) method was developed for quantitative analysis of pristine C₆₀ fullerene. Then, human leukemic cells were incubated with C₆₀ fullerene, homogenized and subjected to the differential centrifugation to retrieve mitochondrial fraction. The C₆₀ fullerene content was quantified by HPLC-ESI-MS in extracts of cellular fractions. This data article refers to the research article "C₆₀ Fullerene Accumulation in Human Leukemic Cells and Perspectives of LED-mediated Photodynam

SUBMITTER: Grebinyk A 

PROVIDER: S-EPMC6141383 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature