Low fasting plasma glucose level as a predictor of new-onset diabetes mellitus on a large cohort from a Japanese general population.

ABSTRACT: Although fasting plasma glucose levels <70 mg/dL are associated with a high incidence of cardiovascular disease (CVD), whether there is any risk of new-onset diabetes mellitus owing to fasting plasma glucose at this range has not been clarified. We measured the odds ratio (OR) of new-onset diabetes mellitus relative to fasting plasma glucose levels at various ranges in a nation-wide Japanese population with and without CVD history. Of 186,749 participants without diabetes in 2008, 171,408 had no history of CVD, while 15,341 did. Participants were classified into 8 categories according to their fasting plasma glucose levels. Unadjusted and multivariable-adjusted logistic regression models were used to measure the OR of new-onset diabetes mellitus in the 3-year follow up. In all participants

SUBMITTER: Ogata E 

PROVIDER: S-EPMC6141503 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature