Using Temporal Expectation to Assess Auditory Streaming in Mice.

ABSTRACT: Auditory streaming is the process by which environmental sound is segregated into discrete perceptual objects. The auditory system has a remarkable capability in this regard as revealed in psychophysical experiments in humans and other primates. However, little is known about the underlying neuronal mechanisms, in part because of the lack of suitable behavioural paradigms in non-primate species. The mouse is an increasingly popular model for studying the neural mechanisms of perception and action because of the range of molecular tools enabling precise manipulation of neural circuitry. Here we present a novel behavioural task that can be used to assess perceptual aspects of auditory streaming in head-fixed mice. Animals were trained to detect a target sound in a one of two simultaneously p

SUBMITTER: Chapuis GA 

PROVIDER: S-EPMC6141755 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature