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Disseminated extrapulmonary Legionella pneumophila infection presenting with panniculitis: case report and literature review.


ABSTRACT:

Background

Legionellosis is a well-known cause of pneumonia. Primary cutaneous and subcutaneous infection caused by Legionella pneumophila is rare and the diagnosis is challenging.

Case presentation

A 38-year-old Thai woman with systemic lupus erythematosus and myasthenia gravis treated with prednisolone and azathioprine presented to our hospital with low-grade fever, diarrhea, and indurated skin lesions on both thighs. Initial examination showed plaques on both inner thighs. Magnetic resonance imaging showed myositis and swelling of the skin and subcutaneous tissue. Diagnosis of panniculitis due to L. pneumophila was carried out by histopathology, Gram stain, and 16S rRNA gene sequencing method of tissue biopsy from multiple sites on both thighs. Myocarditis was diagnosed b

SUBMITTER: Chitasombat MN 

PROVIDER: S-EPMC6142325 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature