Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits.

ABSTRACT:

Background

The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages. It attempts also to compare estimates of inbreeding calculated from ROH (F_ROH), genomic relationship matrix (F_GRM), and pedigree-based coefficient (F_PED).

Results

The average number of ROH per animal was 55.15 ± 13.01 with an average size of 3.24 Mb. The Nellore genome is composed mostly by a high number of shorter segments accounting for 78% of all ROH, although the proportion of the genome covered by them was relatively small. The genome autozygosity proportion indicates moderate to high inbreeding levels for classical sta

SUBMITTER: Peripolli E 

PROVIDER: S-EPMC6142381 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature