The prevalence of submicroscopic Plasmodium falciparum gametocyte carriage and multiplicity of infection in children, pregnant women and adults in a low malaria transmission area in Southern Ghana.

ABSTRACT:

Background

The gametocyte stage of Plasmodium falciparum is considered an important target for disrupting malaria transmission. Indications are that various demographic groups, such as children and pregnant women may differ in risk of harbouring gametocytes, which may be crucial for targeted control. In this study, the relationship between the prevalence and multiplicity of P. falciparum, asexual parasite infections and gametocytaemia was assessed in three different demographic groups in an area of southern Ghana with low malaria endemicity. Levels of antibody responses to Pfs230 were also assessed as a proxy for the presence of gametocytes.

Methods

The study involved multiple cross-sectional sampling of children (N = 184, aged 2-15 years), male and non-pregnant female adult

SUBMITTER: Lamptey H 

PROVIDER: S-EPMC6142636 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature