Development and validation of a new predictive model for breast cancer survival in New Zealand and comparison to the Nottingham prognostic index.

ABSTRACT:

Background

The only available predictive models for the outcome of breast cancer patients in New Zealand (NZ) are based on data in other countries. We aimed to develop and validate a predictive model using NZ data for this population, and compare its performance to a widely used overseas model, the Nottingham Prognostic Index (NPI).

Methods

We developed a model to predict 10-year breast cancer-specific survival, using data collected prospectively in the largest population-based regional breast cancer registry in NZ (Auckland, 9182 patients), and assessed its performance in this data set (internal validation) and in an independent NZ population-based series of 2625 patients in Waikato (external validation). The data included all women with primary invasive breast cancer diagn

SUBMITTER: Elwood JM 

PROVIDER: S-EPMC6142675 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature