Docetaxel increases the risk of severe infections in the treatment of non-small cell lung cancer: a meta-analysis.

ABSTRACT: The purpose of this study was to determine whether docetaxel increases the risk of severe infections in patients with non-small cell lung cancer. A thorough literature search of the PubMed, EMBASE and Cochrane Central Register of Controlled Trials databases was performed (up to February 28, 2017) without any language restrictions. In addition, we searched the www.clinicaltrials.gov website and checked each reference listed in the included studies, relevant reviews and guidelines. We also included randomized controlled trials that reported severe infections in patients with non-small cell lung cancer who were administered docetaxel. A meta- analysis was conducted using relative risk and random effects models in Stata 14.0 software. Sensitivity analysis and meta-regression were performed usi

SUBMITTER: Du Q 

PROVIDER: S-EPMC6142895 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature