Association Between Population Density and Genetic Risk for Schizophrenia.

ABSTRACT:

Importance

Urban life has been proposed as an environmental risk factor accounting for the increased prevalence of schizophrenia in urban areas. An alternative hypothesis is that individuals with increased genetic risk tend to live in urban/dense areas.

Objective

To assess whether adults with higher genetic risk for schizophrenia have an increased probability to live in more populated areas than those with lower risk.

Design, setting, and participants

Four large, cross-sectional samples of genotyped individuals of European ancestry older than 18 years with known addresses in Australia, the United Kingdom, and the Netherlands were included in the analysis. Data were based on the postcode of residence at the time of last contact with the participants. Community-based sa

SUBMITTER: Colodro-Conde L 

PROVIDER: S-EPMC6142911 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature