Association of Cardiovascular Risk Factors With MRI Indices of Cerebrovascular Structure and Function and White Matter Hyperintensities in Young Adults.

ABSTRACT:

Importance

Risk of stroke and brain atrophy in later life relate to levels of cardiovascular risk in early adulthood. However, it is unknown whether cerebrovascular changes are present in young adults.

Objective

To examine relationships between modifiable cardiovascular risk factors and cerebrovascular structure, function, and white matter integrity in young adults.

Design, setting, and participants

A cross-sectional observational study of 125 young adults (aged 18-40 years) without clinical evidence of cerebrovascular disease. Data collection was completed between August 2014 and May 2016 at the University of Oxford, United Kingdom. Final data collection was completed on May 31, 2016.

Exposures

The number of modifiable cardiovascular risk factors at recommende

SUBMITTER: Williamson W 

PROVIDER: S-EPMC6142949 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature