Association of Autistic Traits With Depression From Childhood to Age 18 Years.

ABSTRACT:

Importance

Population-based studies following trajectories of depression in autism spectrum disorders (ASD) from childhood into early adulthood are rare. The role of genetic confounding and of potential environmental intermediaries, such as bullying, in any associations is unclear.

Objectives

To compare trajectories of depressive symptoms from ages 10 to 18 years for children with or without ASD and autistic traits, to assess associations between ASD and autistic traits and an International Statistical Classification of Diseases, 10th Revision (ICD-10) depression diagnosis at age 18 years, and to explore the importance of genetic confounding and bullying.

Design, setting, and participants

Longitudinal study of participants in the Avon Longitudinal Study of Parents and

SUBMITTER: Rai D 

PROVIDER: S-EPMC6143081 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature