Association of Perianal Fistulas with Clinical Features and Prognosis of Crohn's Disease in Korea: Results from the CONNECT Study.

ABSTRACT:

Background/aims

The disease course and factors associated with poor prognosis in Korean patients with Crohn's disease (CD) have not been fully determined. The aim of this study was to explore potential associations between the clinical characteristics and long-term outcomes of CD and perianal fistulas in a Korean population.

Methods

The retrospective Crohn's Disease Clinical Network and Cohort (CONNECT) study enrolled patients diagnosed with CD between July 1982 and December 2008 from 32 hospitals. Those followed for ＜12 months were excluded. Clinical outcomes were CD-related surgery and complications, including nonperianal fistulas, strictures, and intra-abdominal abscesses.

Results

The mean follow-up period was 8.77 years (range, 1.0 to 25.8 years). A total of 1,193

SUBMITTER: Chun J 

PROVIDER: S-EPMC6143449 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature