Classifying atopic dermatitis: protocol for a systematic review of subtypes (phenotypes) and associated characteristics.

ABSTRACT:

Introduction

Atopic dermatitis is a complex disease with differing clinical presentations. Many attempts have been made to identify uniform subtypes, or phenotypes, of atopic dermatitis in order to identify different aetiologies, improve diagnosis, estimate more accurate clinical prognoses, inform treatment andmanagement or predict treatment efficacy andeffectiveness. However, no consensus yet exists on exactly what defines these phenotypes or how many there are and whether they are genuine or statistical artefacts. This review aims to identify previously reported phenotypes of atopic dermatitis, the features used to define them and any characteristics or clinical outcomes significantly associated with them.

Methods and analysis

We will search Ovid Embase, Ovid MEDLINE and W

SUBMITTER: Mulick AR 

PROVIDER: S-EPMC6144401 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature