Selective constraints in cold-region wild boars may defuse the effects of small effective population size on molecular evolution of mitogenomes.

ABSTRACT: Spatial range expansion during population colonization is characterized by demographic events that may have significant effects on the efficiency of natural selection. Population genetics suggests that genetic drift brought by small effective population size (N_e) may undermine the efficiency of selection, leading to a faster accumulation of nonsynonymous mutations. However, it is still unknown whether this effect might be balanced or even reversed by strong selective constraints. Here, we used wild boars and local domestic pigs from tropical (Vietnam) and subarctic region (Siberia) as animal model to evaluate the effects of functional constraints and genetic drift on shaping molecular evolution. The likelihood-ratio test revealed that Siberian clade evolved significantly

SUBMITTER: Chen J 

PROVIDER: S-EPMC6144961 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature