A novel photic entrainment mechanism for the circadian clock in an insect: involvement of c-fos and cryptochromes.

ABSTRACT:

Background

Entrainment to the environmental light cycle is an essential property of the circadian clock. Although the compound eye is known to be the major photoreceptor necessary for entrainment in many insects, the molecular mechanisms of photic entrainment remain to be explored.

Results

We found  that cryptochromes (crys) and c-fos mediate photic entrainment of the circadian clock in a hemimetabolous insect, the cricket Gryllus bimaculatus. We examined the effects of RNA interference (RNAi)-mediated knockdown of the cry genes, Gb'cry1 and Gb'cry2, on photic entrainment, and light-induced resetting of the circadian locomotor rhythm. Gb'cry2 RNAi accelerated entrainment for delay shifts, while Gb'cry1/ Gb'cry2 d

SUBMITTER: Kutaragi Y 

PROVIDER: S-EPMC6145112 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature