Discovery of microRNA-like RNAs during early fruiting body development in the model mushroom Coprinopsis cinerea.

ABSTRACT: Coprinopsis cinerea is a model mushroom particularly suited for the study of fungal fruiting body development and the evolution of multicellularity in fungi. While microRNAs (miRNAs) have been extensively studied in animals and plants for their essential roles in post-transcriptional regulation of gene expression, miRNAs in fungi are less well characterized and their potential roles in controlling mushroom development remain unknown. To identify miRNA-like RNAs (milRNAs) in C. cinerea and explore their expression patterns during the early developmental transition of mushroom development, small RNA libraries of vegetative mycelium and primordium were generated and putative milRNA candidates were identified following the standards of miRNA prediction in animals and plants. Two out of 22 nove

SUBMITTER: Lau AYT 

PROVIDER: S-EPMC6145500 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature