Association of Nodal Metastasis and Mortality With Vermilion vs Cutaneous Lip Location in Cutaneous Squamous Cell Carcinoma of the Lip.

ABSTRACT:

Importance

Although the lip is considered a high-risk location in cutaneous squamous cell carcinoma (cSCC), it has not been established whether this risk stems from vermilion or cutaneous locations or both.

Objective

To compare differences in risks of recurrence, metastasis, and death from cSCCs on the vermilion vs cutaneous lip.

Design, setting, and participants

Retrospective cohort study of 303 patients with 310 primary cSCCs of the lip (138 cutaneous, 172 vermilion) diagnosed between 2000 and 2015 at 2 academic tertiary care centers in Boston, Massachusetts.

Main outcomes and measures

Development of local recurrence, nodal metastasis, distant metastasis, disease-specific death, and all-cause death.

Results

Of the 303 study participants with 310 SCCs o

SUBMITTER: Wang DM 

PROVIDER: S-EPMC6145652 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature