Association Between Muscular Strength and Cognition in People With Major Depression or Bipolar Disorder and Healthy Controls.

ABSTRACT:

Importance

Objective physical fitness measures, such as handgrip strength, are associated with physical, mental, and cognitive outcomes in the general population. Although people with mental illness experience reduced physical fitness and cognitive impairment, the association between muscular strength and cognition has not been examined to date.

Objective

To determine associations between maximal handgrip strength and cognitive performance in people with major depression or bipolar disorder and in healthy controls.

Design, setting, and participants

In a multicenter, population-based study conducted between February 13, 2005, and October 1, 2010, in the United Kingdom, cross-sectional analysis was conducted of baseline data from 110 067 participants in the UK Biobank.

SUBMITTER: Firth J 

PROVIDER: S-EPMC6145677 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature