Association of Obstructive Sleep Apnea With Calvarial and Skull Base Thinning.

ABSTRACT: Importance:Spontaneous cerebrospinal fluid leaks (sCSF-L) of the temporal bone are associated with obesity, calvarial thinning, and obstructive sleep apnea (OSA), and the incidence has doubled in the past decade. It is currently unknown if OSA is independently associated with skull thinning. Objective:To determine if patients with OSA have thinner skulls than patients without OSA. Design, Setting, and Participants:A retrospective cohort study of patients who underwent a level 1 polysomnogram (PSG) and also had high-resolution computed tomographic (CT) imaging of the head from January 2010 to March 2017 at Indiana University was carried out. Patients with moderate to severe OSA (apnea-hypopnea index [AHI]≥25/h) and without OSA (AHI<5/h) were matched for age and body mass index (BMI, calcula

SUBMITTER: Rabbani C 

PROVIDER: S-EPMC6145742 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature