Consanguineous Marriage and the Psychopathology of Progeny: A Population-wide Data Linkage Study.

ABSTRACT:

Importance

Approximately 1 in 10 children worldwide are born to consanguineous parents. The literature on consanguinity and mental health of progeny is scarce despite the fact that many of the factors associated with consanguineous unions are also associated with mental health.

Objective

To investigate if children of consanguineous parents are at increased risk of common mood disorders or psychoses.

Design, setting, and participants

This investigation was a retrospective population-wide cohort study of all individuals born in Northern Ireland between January 1, 1971, and December 31, 1986, derived from the Child Health System data set and linked to nationwide administrative data sources on prescription medication and death records. Data from the Child Health System da

SUBMITTER: Maguire A 

PROVIDER: S-EPMC6145769 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature