Multi-unit relations among neural, self-report, and behavioral correlates of emotion regulation in comorbid depression and obesity.

ABSTRACT: Depression is a leading cause of disability and is commonly comorbid with obesity. Emotion regulation is impaired in both depression and obesity. In this study, we aimed to explicate multi-unit relations among brain connectivity, behavior, and self-reported trait measures related to emotion regulation in a comorbid depressed and obese sample (N = 77). Brain connectivity was quantified as fractional anisotropy (FA) of the uncinate fasciculi, a white matter tract implicated in emotion regulation and in depression. Use of emotion regulation strategies was assessed using the Emotion Regulation Questionnaire (ERQ). We additionally measured reaction times to identifying negative emotions, a behavioral index of depression-related emotion processing biases. We found that greater right uncinate fas

SUBMITTER: Pines AR 

PROVIDER: S-EPMC6145883 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature