Urinary biomarker panel for diagnosing patients with depression and anxiety disorders.

ABSTRACT: Available data indicate that patients with depression and anxiety disorders are likely to be at greater risk for suicide. Therefore, it is important to correctly diagnose patients with depression and anxiety disorders. However, there are still no empirical laboratory methods to objectively diagnose these patients. In this study, the multiple metabolomics platforms were used to profile the urine samples from 32 healthy controls and 32 patients with depression and anxiety disorders for identifying differential metabolites and potential biomarkers. Then, 16 healthy controls and 16 patients with depression and anxiety disorders were used to independently validate the diagnostic performance of the identified biomarkers. Finally, a panel consisting of four biomarkers-N-methylnicotinamide, aminom

SUBMITTER: Chen JJ 

PROVIDER: S-EPMC6145889 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature