Ontology highlight
ABSTRACT:
SUBMITTER: Marcu R
PROVIDER: S-EPMC6147238 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
iScience 20180509
The endothelium first forms in the blood islands in the extra-embryonic yolk sac and then throughout the embryo to establish circulatory networks that further acquire organ-specific properties during development to support diverse organ functions. Here, we investigated the properties of endothelial cells (ECs), isolated from four human major organs-the heart, lung, liver, and kidneys-in individual fetal tissues at three months' gestation, at gene expression, and at cellular function levels. We s ...[more]